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#Human japanese intermediate trial plus
#Human japanese intermediate trial free

3–7 The extent to which response and survival benefits with immunotherapy-based regimens persist after long-term follow-up will inform optimal first-line treatment options.

#Human japanese intermediate trial plus

1 2 First-line aRCC treatments include the dual immune checkpoint inhibitor combination nivolumab plus ipilimumab (NIVO+IPI) as well as immunotherapy–tyrosine kinase inhibitor combinations, with numerous novel regimens under investigation. Recent approvals of immunotherapy-based regimens have revolutionized the treatment of patients with advanced renal cell carcinoma (aRCC). 34 Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.33 Bristol Myers Squibb, Princeton, New Jersey, USA.32 Departments of Urology and Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.31 Department of Medical Oncology, Levine Cancer Institute, Atrium Health, Charlotte, North Carolina, USA.30 Department of Oncology, Herlev Hospital, Copenhagen, Denmark.29 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.28 Oncology Institute, Shamir Medical Center, Be'er Yaakov, Israel.27 Department of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.26 Department of Medical Oncology, Westmead Hospital, Sydney, New South Wales, Australia.25 Department of Urology, Jena University Hospital, Jena, Germany.24 Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.23 Department of Medicine, Division of Medical Oncology, University of Washington, Seattle, Washington, USA.22 Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.21 Instituto Oncológico Fundación Arturo López Pérez, Santiago, Chile.Rini is now with the Department of Medicine, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA

19 Department of Hematology and Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio, USA.

18 Department of Medical Oncology, Dana-Farber Cancer Institute, The Lank Center for Genitourinary Oncology, Boston, Massachusetts, USA.

17 Department of Medical Oncology, Bordeaux University Hospital, Bordeaux, France.

16 Tel Aviv University, Tel Aviv, Israel.

15 Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel.

14 Department of Internal Medicine, University of Pavia, Pavia, Italy.

13 Clinic for Medical Oncology and Clinic for Urology, Essen University Hospital, Essen, Germany.

12 Interdisciplinary Genitourinary Oncology, West German Cancer Center Essen, Essen, Germany.

11 Divisions of Medical Oncology and Urology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.

10 Division of Hematology and Oncology, UT Southwestern Kidney Cancer Program, Dallas, Texas, USA.9 Department of Medical Oncology, Hôpitaux Universitaires de Strasbourg / ICANS, Strasbourg, France.8 Department of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.7 Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.

#Human japanese intermediate trial free

6 Department of Genitourinary Oncology, Barts Cancer Institute, Cancer Research UK Experimental Cancer Medicine Centre, Queen Mary University of London, Royal Free National Health Service Trust, London, UK.5 Department of Oncology, Palacky University, and University Hospital Olomouc, Olomouc, Czech Republic.4 Centro de Investigación Clínica Bradford Hill, Santiago, Chile.3 Department of Medicine, Beth Israel Deaconess Medical Center, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts, USA.2 Department of Medical Oncology, Gustave Roussy, Villejuif, France.

1 Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.